- 簡(jiǎn)介
- 科研領(lǐng)域
- 學(xué)術(shù)發(fā)表
個(gè)人簡(jiǎn)介
2013年09月-2017年07月，中科院上海生科院植物逆境生物學(xué)研究中心，博士
2017年07月-2021年07月，中科院分子植物科學(xué)卓越創(chuàng)新中心，博士后
2021年07月-至今，北京大學(xué)現(xiàn)代農(nóng)業(yè)研究院 質(zhì)譜分析平臺(tái)負(fù)責(zé)人
教育經(jīng)歷
工作經(jīng)歷
科研領(lǐng)域
現(xiàn)代質(zhì)譜儀擁有更快的掃描速度和超高的分辨率，已被廣泛用于生命科學(xué)研究的多個(gè)領(lǐng)域。色譜質(zhì)譜聯(lián)用儀是當(dāng)前高通量測(cè)定生物體內(nèi)蛋白質(zhì)組和代謝組變化的最佳分析設(shè)備，是系統(tǒng)生物學(xué)研究不可或缺的重要工具。
北京大學(xué)現(xiàn)代農(nóng)業(yè)研究院質(zhì)譜分析平臺(tái)擁有多種質(zhì)譜分析儀器，包括超高分辨率液相色譜質(zhì)譜分析系統(tǒng)、三重四極桿氣相色譜質(zhì)譜分析系統(tǒng)等。我們依托院質(zhì)譜分析平臺(tái)，以農(nóng)作物為主要分析樣本，開(kāi)發(fā)適用于現(xiàn)代農(nóng)業(yè)基礎(chǔ)研究的質(zhì)譜分析技術(shù)，并著力構(gòu)建主要農(nóng)作物蛋白質(zhì)組以及代謝組數(shù)據(jù)庫(kù)。我們的主要研究方向包括作物蛋白質(zhì)組學(xué)和代謝組學(xué)分析方法開(kāi)發(fā)，農(nóng)作物重要品質(zhì)的質(zhì)譜檢測(cè)分析，關(guān)鍵農(nóng)藝性狀的多組學(xué)大隊(duì)列深度分析，為現(xiàn)代農(nóng)業(yè)發(fā)展提供分析技術(shù)支撐。
學(xué)術(shù)發(fā)表
1. Guochen Qin, Menghuan Qu, Bei Jia, Wei Wang, Zhoujun Luo, Chun-Peng Song, W. Andy Tao, Pengcheng Wang. FAT-switch-based quantitative S-nitrosoproteomics reveals a key role of GSNOR1 in regulating ER functions. 2023, Nature communications, 2023, 14, 3268. https://doi.org/10.1038/s41467-023-39078-0.
2. Chenglin Jiang. Ju Sun, Rui Li, Shijuan Yan, Wei Chen, Liang Guo, Guochen Qin, Pengcheng Wang, Cheng Luo, Wenjie Huang, Qinghua Zhang, Alisdair R. Fernie, David Jackson, Xiang Li, Jianbing Yan. A reactive oxygen species burst causes haploid induction in maize. Molecular Plant. 2022, 15(6):943-955. doi: 10.1016/j.molp.2022.04.001. PMID: 35395409.
3. Mingjing Wang, Hailong Zhang, Xiaonan Zhao, Jingwen Zhou, Guochen Qin, Yuqi Liu, Xiaoyue Kou, Zhenjie Zhao, Tao Wu, Jian-Kang Zhu, Xianzhong Feng, Lixin Li. SYNTAXIN OF PLANTS81 regulates root meristem activity and stem cell niche maintenance via ROS signaling. Plant Physiology. 2022, kiac530. doi: 10.1093/plphys/kiac530. PMID: 36427205.
4. Quanzi Bai?, Wenjing Yang? (co-first author), Guochen Qin, Baolin Zhao, Liangliang He, Xuan Zhang, Weiyue Zhao, Dian Zhou, Ye Liu, Yu Liu, Hua He, Million Tadege, Yan Xiong, Changning Liu, Jianghua Chen. Multidimensional Gene Regulatory Landscape of Motor Organ Pulvinus in the Model Legume Medicago truncatula. International Journal of Molecular Sciences. 2022, 23(8):4439. doi: 10.3390/ijms23084439. PMID: 35457256.
5. Liwen Fu?, Yanlin Liu? (co-first author), Guochen Qin, Ping Wu, Hailing Zi, Zhongtian Xu, Xiaodi Zhao, Yue Wang, Yaxing Li, Shuhui Yang, Chao Peng, Catherine C.L. Wong, Sang-Dong Yoo, Renyi Liu, Young-Hee Chu, Yan Xiong. The TOR-EIN2 axis mediates nuclear signaling to modulate plant growth. Nature, 2021, 591. https://doi.org/10.1038/s41586-021-03310-y
6. Jie Yang, Hang He, Yuming He, Qiaozhen Zheng, Qingzhong Li, Guochen Qin, Pengchen Wang, Chao Peng, Yangtao Gu, Yang Zhao, Mingzhang Wen, Rong Chen, Tongda Xu. TMK1-based auxin signaling regulates abscisic acid responses via phosphorylating ABI1/2 in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (24). https://doi.org/10.1073/pnas.2102544118
7. Li Guan, Shurui Yang, Shenglin Li, Yu Liu, Yuqi Liu, Yi Yang, Guochen Qin, Haihai Wang, Tao Wu, Zhigang Wang, Xianzhong Feng, Yongrui Wu, Jian-Kang Zhu, Xugang Li, Lixin Li. AtSEC22 Regulates Cell Morphogenesis via Affecting Cytoskeleton Organization and Stabilities. Frontiers in Plant Science, 2021, 12: 635732. DOI: 10.3389/fpls.2021.635732
8. Qian Wang?, Guochen Qin? (co-first author), Min Cao, Rong Chen, Yuming He, Liyuan Yang, Zhejun Zeng, Yongqiang Yu, Yangtao Gu, Weiman Xing, W. Andy Tao, Tongda Xu. A phosphorylation-based switch controls TAA1-mediated auxin biosynthesis in plants. Nature Communications, 2020, 11, 679. https://doi.org/10.1038/s41467-020-14395-w
9. Pan Liu, Wen-Feng Nie, Xiansong Xiong, Yuhua Wang, Yuwei Jiang, Pei Huang, Xueqiang Lin, Guochen Qin, Huan Huang, Qingfeng Niu, Jiamu Du, Zhaobo Lang, Rosa Lozano-Duran, Jian-Kang Zhu. A novel protein complex that regulates active DNA demethylation in Arabidopsis.Journal of Integrative Plant Biology, 2020. https://doi.org/10.1111/jipb.13045
10. Guochen Qin, Jun Ma, Xiaomei Chen, Zhaoqing Chu, Yi-Min She. Methylated-antibody affinity purification to improve proteomic identification of plant RNA polymerase Pol V complex and the interacting proteins. Scientific Reports, 2017, 7: 42943
11.Jingjing Fang, Guochen Qin, Jun Ma, Yi-Min She. Quantification of plant cell wall monosaccharides by reversed-phase liquid chromatography with 2-aminobenzamide pre-column derivatization and a non-toxic reducing reagent 2-picoline borane. Journal of Chromatography A, 2015, 1414:122-128
12. Guochen Qin, Qitian Wang, Jin Hu, Zhan Li, Fei He, Jiancheng Wang. Changes in seed quality and ABA content during seed development in sponge gourd (Luffa cylindrica). Seed Science and Technology, 2013, 41: 398-406.