個(gè)人簡介

2008–2015，美國愛荷華州立大學(xué) （Iowa State University），理學(xué)博士

2015–2020，美國馬里蘭大學(xué) (University of Maryland, College Park)，博士后

2021—，北京大學(xué)現(xiàn)代農(nóng)業(yè)研究院，研究員, 草莓發(fā)育生物學(xué)與種質(zhì)資源創(chuàng)新研究組PI，泰山學(xué)者青年專家

主要研究領(lǐng)域

草莓是世界上最重要的小漿果之一，是現(xiàn)代“都市農(nóng)業(yè)”的典型代表。其中我國的草莓種植面積（268萬畝）和產(chǎn)量（500萬噸）都居世界首位。草莓具有果實(shí)結(jié)構(gòu)獨(dú)特（假果）、生長周期相對(duì)較短(4-6月)、多年生、可以無性繁殖(匍匐莖)等特點(diǎn)，特別是近年來隨著二倍體森林草莓基因組注釋的完善、轉(zhuǎn)基因體系的建立和CRISPR/Cas9技術(shù)的開發(fā)，二倍體森林草莓逐漸發(fā)展成為研究非呼吸躍變型果實(shí)發(fā)育、匍匐莖發(fā)育的一種模式物種。懸鉤子屬（Rubus）樹莓具有豐富的種質(zhì)資源且多為二倍體，基因組小（300Mb)，其果實(shí)富含SOD、鞣花酸和各種維生素，具有抗氧化、抗衰老、抗癌癥、預(yù)防心血管疾病等生理活性，但是在我國的普及程度仍舊十分落后。課題組以森林草莓、栽培草莓和樹莓為主要研究對(duì)象，當(dāng)前主要研究工作：(1). 草莓肉質(zhì)果發(fā)育起始及薔薇科果實(shí)作物肉質(zhì)果發(fā)育多樣性的遺傳機(jī)制；(2). 草莓樹莓果實(shí)品質(zhì)調(diào)控的分子機(jī)制，高品質(zhì)果實(shí)新種質(zhì)的創(chuàng)制；(3). 草莓主要真菌病害（灰霉病、白粉病）的致病機(jī)理及分子抗病育種策略的開發(fā)；(4). 樹莓發(fā)育過程中各種特征性狀（刺、果核等）發(fā)育的分子機(jī)制解析，助推我國樹莓的種質(zhì)創(chuàng)新和產(chǎn)業(yè)發(fā)展；(5). 園藝作物基因編輯體系的優(yōu)化及應(yīng)用；以基因編輯為基礎(chǔ)的草莓樹莓分子設(shè)計(jì)育種策略開發(fā)。

代表性論文（# equal contribution; *corresponding）

14、Zhang, C.#, Tang, Y.#, Tang, S.#, Chen, L., Yuan, H., Xu, Y., Zhou, Y., Zhang, S., Wang, J., Wen, H., Jiang, W., Pang, Y., Deng, X., Cao, X., Zhou, J.*, Song, X.* and Liu, Q.*. (2024). An Inducible CRISPR-activation tool for accelerated plant regeneration. Plant Communications, https://www. sciencedirect.com/science/article/pii/S2590346224000439?via%3Dihub 

13、Zhou, J. #, Li, M. #, Li, Y., Xiao, Y., Luo,X., Gao, S., Ma,Z., Sadowski,N., Timp, W., Dardick, C., Callahan, A., Mount, S., Liu, Z. (2023). Comparison of red raspberry and wild strawberry fruits reveals mechanisms of fruit type specification. Plant Physiology, kiad409. https://doi.org/10.1093 /plphys/kiad409.

12、Ma, Z., Ma, L., Zhou, J.* (2023). Applications of CRISPR/Cas genome editing in economically important fruit crops: recent advances and future directions. Molecular Horticulture. https://molhort. biomedcentral.com/articles/10.1186/s43897-023-00049-0.

11、Zhou, J., Sittmann, J., Guo, L., Xiao Y., Huang, X., Pulapaka, A., and Liu, Z. (2020). Gibberellin and auxin signaling genes RGA1 and ARF8 repress accessory fruit initiation in diploid strawberry. Plant Physiology, 185, 1059-1075.

10、Zhou, J., Li, D., Wang, G., Wang F., Kunjal, M., Joldersma, D. and Liu, Z. (2019). Application and future perspective of CRISPR/Cas9 genome editing in fruit crops. Journal of Integrative Plant Biology, 62, 269-286. 

9、Zhou, J., Wang, G. and Liu, Z. (2018). Efficient genome-editing of wild strawberry genes, vector development, and validation. Plant Biotechnology Journal, 16, 1868-1877. 

8、Zhou, J., Peng, Z., Long, J., Sosso, D., Liu, B., Eom, J., Zhou, H., Huang, S., Cruz, C., Frommer, W., White, F. and Yang, B. (2015). Gene Targeting by the TAL Effector PthXo2 Reveals Cryptic Resistance Gene for Bacterial Blight of Rice. The Plant Journal, 82, 632-643.

7、Antony, G. #, Zhou, J. #, Huang, S., Li, T., Liu, B., White, F., and Yang, B. (2010). Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3. The Plant Cell, 22, 3864-3876.

6、Zhou, J., Song Y., Zhang Y. (2008). Advancement of Late Blight Resistance Genes in Potato. Biotechnology Bulletin, 5, 13-17.

5、Chen, G., Xu, P., Pan, J., Li, Y., Zhou, J., Kuang, H., Lian, H. (2020). Inhibition of FvMYB10 transcriptional activity promotes color loss in strawberry fruit. Plant Science, https://doi.org/10.1016/j.plantsci.2020. 110578

4、Wight, H., Zhou, J., Li, M., Hannenhalli, S., Mount, S. and Liu, Z. (2019). Draft Genome Assembly and Annotation of Red Raspberry Rubus Idaeus.  (BioRxiv: https://www.biorxiv.org/content/10.1101/ 546135v2).

3、Long, J., Song, C., Yan, F., Zhou, J., Zhou, H. and Yang, B. (2018) Non-TAL Effectors from Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice. Frontiers in Plant Science. 9:1857. https://doi: 10.3389/fpls.2018.01857.

2、 Li T., Huang S., Zhou J., Yang B. (2013). Designer TAL Effectors Induce Disease Susceptibility and Resistance to Xanthomonas oryzae pv. oryzae in Rice. Molecular Plant, 6, 781-789.

1、Song Y., Zhou, J., Zhang Y. (2007). Advancement of Tissue-specific Promoter in Plants. Biotechnology Bulletin, 6, 21-24.