報(bào)告題目:A genomic roadmap to breed better vegetables
報(bào)告時(shí)間:2016年10月13日 16:00 ——17:00
報(bào)告人簡(jiǎn)介:
黃三文博士于2005年畢業(yè)于荷蘭瓦格寧根大學(xué),同年回國(guó),在中國(guó)農(nóng)業(yè)科學(xué)院蔬菜花卉研究所建立實(shí)驗(yàn)室,2013年被任命為深圳農(nóng)業(yè)基因組研究所co-founding director,在蔬菜基因組方面的研究處于國(guó)際領(lǐng)先的水平。他目前的主要研究方向是黃瓜、馬鈴薯、番茄的生物學(xué)和基因組學(xué)。他的工作發(fā)表到 Science, Nature, Nature Genetics 等國(guó)際知名期刊,引用量超過 5000 。
報(bào)告內(nèi)容簡(jiǎn)介:
Next generation sequencing technologies and the associated informatics are transforming biology into big data science. Vegetables are essential for human health and their production constitutes a major section in rural economy, but genomic resource for vegetable breeding was scarce. To overcome this limitation, my lab coordinated and participated de novo genome sequencing several major vegetable crops, including cucumber, tomato, and potato. We also construct genome variation maps for cucumber and tomato, providing millions SNP for molecular breeding. In total, so far we generated 40 Tbps genomic data. We integrated this big data with molecular biology and biochemistry to discover the mechanisms of several biological and evolutionary processes, including domestication of cucumber and tomato, sex determination and fruit elongation in cucumber, and flavor metabolism in tomato. These studies enable a molecular design of a cucumber genotype with bitter foliage for insect resistance and nonbitter fruits even under stress, as well as a tomato cultivar with higher sugar content and pleasant flavor. Furthermore, we are pursuing to re-domesticate potato by genome design, an initiative to transform the tuber-propagated autopolyploid that is difficult for breeding and logistics, into a breeder- and environment- friendly crop that is a diploid and propagated by true seeds.